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View PaperRole of Disease Progression Models in Drug Development
Jeffrey S. Barrett, Tim Nicholas, Karim Azer, Brian W. Corrigan
Pharmaceutical Research | April 2022
The use of Disease progression models (DPMs) in Drug Development has been widely adopted across therapeutic areas as a method for integrating previously obtained disease knowledge to elucidate the impact of novel therapeutics or vaccines on disease course, thus quantifying the potential clinical benefit at different stages of drug development programs. This paper provides a…